Role of transporter proteins in bile tolerance of Lactobacillus acidophilus.

نویسندگان

  • Erika A Pfeiler
  • Todd R Klaenhammer
چکیده

Lactobacillus acidophilus NCFM derivatives containing deletion mutations in the transporter genes LBA0552, LBA1429, LBA1446, and LBA1679 exhibited increased sensitivity to bile. These strains showed unique patterns of sensitivity to a variety of inhibitory compounds, as well as differential accumulations of ciprofloxacin and taurocholate.

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 75 18  شماره 

صفحات  -

تاریخ انتشار 2009